PE-22-28 5mg
Potent TREK-1 potassium channel blocker from the spadin family. ≥98% purity, 5 mg lyophilized. For laboratory research only.
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Description
Research Profile
TREK-1 (TWIK-related potassium channel-1) is a two-pore domain potassium channel implicated in mood regulation and neuroplasticity research. PE-22-28 demonstrates high-affinity TREK-1 inhibition, and published studies have investigated its effects on hippocampal neurogenesis, BDNF-TrkB signaling, and serotonergic neurotransmission, positioning it as a valuable tool in neuroscience research.











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